I.      Buzzer Quiz

1.       The mammary gland is anchored to a muscle by the Cooper ligament. What is the name of this muscle?

n  Answer：Pectoralis major muscle

 

2.       The parasympathetic nerve of the facial nerve innervates submandibular gland, sublingual gland and what structure?

n  Answer：Lacrimal gland

 

3.       What is the structure of inner ear which detects vertical linear acceleration?

n  Answer：Saccule

 

4.       What is the subtype of adrenergic receptor that is related to the therapeutic for bronchial asthma?

n  Answer：β₂ receptor

 

5.       What is the name of the phenomenon that the action potential is conducted through the axons of myelinated nerve fibers?

n  Answer：saltatory conduction

 

6.       What is the name of the hormone which is produced by 5α-reductase and is indispensable for development of male external genitalia?

n  Answer：Dihydrotestosterone

 

7.       What is the enzyme that determines the metabolic rate by making metabolic reaction slow?

n  Answer：Rate limiting enzyme

 

8.       Auditory nerve fibers have different thresholds of action potential depending on frequency of sound. What is the name of the sound frequency for which the threshold is lowest?

n  Answer：Characteristic frequency

 

9.       What is the subclass change of immunoglobulin in B cells while retaining antigen specificity?

n  Answer：Class switch

 

 

10.    What is the substance whose serum level decreases in nephrotic syndrome, resulting in edema?

n  Answer：Albumin

 

11.    What is the name of the body cell of nerve fiber in corticospinal tract?

n  Answer：Betz (giant) cell / giant pyramidal cell

 

12.    What is the liquid component separated by leaving the blood in the test tube?

n  Answer：serum

 

13.    What is the hormone secreted from pancreatic δ cells and suppresses the secretion of insulin or glucagon？

n  Answer：Somatostatin

 

14.    What is the protein activated by the thrombin / thrombomodulin complex in the anticoagulant system?

n  Answer：Protein C

 

15.    What is the factor that binds to unwanted proteins and is important for selective degradation in the proteasome?

n  Answer：Ubiquitin

 

16.    What is the target molecule of mono clonal antibody which was found by research team of Tasuku Honjo in Kyoto university and developed as a remedy for malignant melanoma?

n  Answer：PD-1

 

17.    What is the cell adhesion molecule which splits exfoliative toxin?

n  Answer：Desmoglein-1

 

18.    What is the peripheral chemoreceptor which controls ventilation volume through glossopharyngeal nerve?

n  Answer：Carotid body

 

19.    What is the name of the second messenger when nerve fiber in substantia nigra compacta acts on the receptor in direct pathway of striatum?

n  Answer：cAMP

 

 

20.    When injuring neural fiber, the axons and myelins of peripheral part degenerate. What is this phenomenon?

n  Answer：Waller degeneration

 

 

II.    Flip Quiz

1.       Choose 3 of the following functions of the organ shown in this figure.

【Picutre：Tissue of the kidney】

①      Regulation of circulating plasma volume

②      Secretion of aldosterone

③      Synthesis of albumin

④      Activation of vitamin D

⑤      Regulation of blood acid-base balance by ammonia production

⑥      Secretion of angiotensin converting enzyme(ACE)

n  Answer：①・④・⑤

 

2.       The shoulder joint is stable even though the glenoid fossa is not large enough for the humeral head to fit in. Choose four of the following main muscles that stabilize the shoulder joint.

①      Pectoralis major muscle

②      Subscapularis muscle

③      Latissimus dorsi muscle

④      Teres minor muscle

⑤      Infraspinatus muscle

⑥      Supraspinatus muscle

⑦      Serratus anterior muscle

⑧      Biceps brachii muscle

n  Answer：②・④・⑤・⑥

n  Comment：The structure that stabilizes the shoulder joint by these four skeletal muscles is called a rotator cuff. The most frequent injury of the cuff tendons occurs in supraspinatus muscle.

 

 

3.       cAMP is the second messenger in the intracellular signal transduction system. State increased(↑)/decreased(↓) in intracellular cAMP concentration in activation of the following receptors.

①      β₁ receptor

②      β₂ receptor

③      D₁ receptor

④      D₂ receptor

n  Answer：① Increased　② Increased　③ Increased  ④ Decreased

n  Comment：As all β receptors are conjugated with Gs protein, adenylate cyclase is activated and the cAMP concentration increases. On the other hand, D2 receptor is conjugated with Gi protein and suppresses adenylate cyclase.

 

4.       Arrange the following coagulation factors in correct order according to the activation order in coagulation cascade.

①      Ⅸ factor

②      Ⅹ factor

③      Ⅺ factor

④      Ⅻ factor

n  Answer：④ → ③ → ① → ②

 

5.       Arrange the normal tissue structure of the epidermis in order from the basement membrane side.

①      Stratum corneum

②      Stratum granulosum

③      Stratum basale

④      Stratum spinosum

n  Answer：③ → ④ → ② → ①

 

6.       Na 143 mEq / L, K 2.7 mEq / L, Cl 114 mEq / L, HCO 3 - 18 mEq / L  Calculate the anion gap.

n  Answer：11 mEq / L

 

 

 

III.Time Attack

①     　　　　　　　　　　　　

1.       The left subclavian artery is a branch from the Aorta.

n  Answer：True

 

2.       Concentration of serum potassium increases by inhibiting angiotensin receptors.

n  Answer：True

 

3.       IgG is the main immunoglobulin in human colostrum.

n  Answer：False

 

4.       Thyroid Stimulating Hormone is produced in the posterior lobe of pituitary gland.

n  Answer：False

 

5.       Vital capacity is equal to total lung capacity minus functional residual capacity.

n  Answer：False

 

6.       Carcinogenesis caused by radiation is a deterministic effect.

n  Answer：False

 

7.       Which of the following neurotransmitters is inhibiting?

P)     GABA            

Q)    Dopamine

R)     Acetylcholine

S)      Serotonin

n  Answer：P

 

 

 

 

 

 

8.       Which of the following has NO HLA?

P)     Glomerulus

Q)    Red Blood Cell

R)     Plasma cell

S)      Endothelial cell

n  Answer：Q

 

9.       Choose the correct movement which occurs during inhalation.

P)     Concentration of the abdominal wall muscle

Q)    Downward movement of ribs

R)     Relaxation of diaphragm

S)      Concentration of the external intercoastal muscle

n  Answer：S

 

10.    Which immunologic cell matures in the thymus?

P)     B cell

Q)    Macrophage

R)     T cell

S)      Neutrophil

n  Answer：R

 

11.    Which of the following symptoms is observed in right heart failure?

P)     Palpitation

Q)    Orthopnea

R)     Over swelling of jugular vein

S)      Vertigo

n  Answer：R

 

12.    Which of the following diseases causes delta wave in electrocardiogram?

P)     WPW syndrome

Q)    Atrial premature contraction(APC)

R)     Paroxysmal supraventricular tachycardia(PSVT)

S)      Atrioventricular recurrent tachycardia(AVRT)

n  Answer：P

 

 

 

 

13.    Which of the following is NOT the risk factor for breast cancer?

P)     Postmenopausal obesity

Q)    Family history of breast cancer

R)     Radiation

S)      Progesterone

n  Answer：S

P) Aromatase in fat cell promotes estrogen and causes high estrogen environment. But premenopausal obesity decreases risk.

S) Progesterone competes with estrogen.

 

14.    Name the nerve which innervates the superior oblique muscle

n  Answer：trochlear nerve

 

15.    The contractile force of the myocardium increases as the myocardium is stretched. What law is this?

n  Answer：Stirling's law

 

16.    How much calorie is obtained from 1 g of alcohol?

n  Answer：7kcal/g

 

17.    What is the type of the epithelium of the stomach and duodenum?

n  Answer：Simple columnar epithelium

 

18.    What is the rapidly increasing pituitary hormone just before ovulation?

n  Answer：Luteinizing hormone (LH)

 

19.    What is the change in the pupil due to oculomotor paralysis?

n  Answer：Mydriasis

 

20.    What is called a common site of nasal bleeding?

n  Answer：Kieselbach region

 

 

 

 

 

 

 

②     　　　　　　　　　　　　

1.       There are seven pairs of cervical spinal nerves.

n  Answer：False

 

2.       A person with 60 percent body water has 40 percent of extracellular fluid. 

n  Answer：False

 

3.       Type Ⅲ hypersensitivity is related to accumulation of immunocomplex.

n  Answer：True

 

4.       Elevation of blood calcium promotes calcitonin secretion.

n  Answer：True

 

5.       Hemoglobin F has higher oxygen affinity than hemoglobin A.

n  Answer：True

 

6.       CD20 positive CD4⁺ T cell has immunosuppression effect.

n  Answer：False

 

7.       Which of the following factors determines the preload of the heart?

P)     Peripheral vascular resistance

Q)    Myocardial contractility

R)     Venous return

S)      Pulmonary artery pressure

n  Answer：R

 

8.       Which cell is a member of natural immune system?

P)     CD4⁺ T cell

Q)    NK cell

R)     Plasma cell

S)      CD8⁺ T cell

n  Answer：Q

 

 

 

 

 

9.       Which one of the following cannot be measured by a spirometer?

P)     Residual Volume(RV)

Q)    Vital capacity(VC)

R)     Tidal volume(TV)

S)      Inspiratory reserve volume(IRV)

n  Answer：P

 

10.    Which of the following symptoms is caused by collateral circulation of decompensated cirrhosis?

P)     Edema

Q)    Esophageal varices

R)     Gynecomastia

S)      Ascites

n  Answer：Q

 

11.    Which of the following segment reabsorbs the majority of amino acids?

P)     Proximal tubule

Q)    Henle loop

R)     Distal tubule

S)      Collecting duct

n  Answer：P

 

12.    Which of the following lingual papillae is the most numerous?

P)     Vallate papillae

Q)    Filiform papillae

R)     Foliate papillae

S)      Fungiform papillae

n  Answer:：Q

 

13.    Which of the following reflex is impaired in a patient with cervical cord injury 2 months after injury?

P)     Corneal reflex

Q)    Abdominal reflex

R)     Patellar tendon reflex

S)      Achilles tendon reflex

n  Answer：Q

 

 

 

 

14.    What hormone is secreted from pancreatic β cells?

n  Answer：Insulin

 

15.    What is the remnant of the umbilical vein?

n  Answer：Hepatic streak / Round ligament of the liver

 

16.    What is the calorific value obtained from 1 g of lipid?

n  Answer：9kcal/g

 

17.    What is the base included in the RNA but not included in the DNA?

n  Answer：Uracil (U)

 

18.    What are the organs that sense the extension of skeletal muscle?

n  Answer：Muscle spindle

 

19.    What is the structure that connects the tympanic chamber and the pharynx?

n  Answer：Auditory tube (Eustachian tube)

 

20.    What is the cytoskeleton which is connected to the cadherin?

n  Answer：Actin filament

 

 

③     　　　　　　　　　　　　

1.       Mandibular nerve passes through the round foramen.

n  Answer：False

 

2.       Insulin receptor is a G protein coupled receptor.

n  Answer：False

 

3.       TypeⅡ diabetes is an autoimmune disease.

n  Answer：False

 

4.       People with type A blood have anti-B antibody in the serum.

n  Answer：True

 

5.       The pulmonary surfactant tends to collapse alveoli.

n  Answer：False

6.       Contrast enhanced CT shouldn’t be conducted before thyroid scintigraphy.

n  Answer：True

 

7.       Where is the origin of myocardial action potential?

P)     Sinoatrial node

Q)    Atrioventricular node

R)     His bundle

S)      Purkinje’s fiber

n  Answer：P

 

8.       Which antibody passes through the human placenta?

P)     IgM

Q)    IgE

R)     IgG

S)      IgA

n  Answer：R

 

9.       Where does fertilization occur?

P)     Uterine body part

Q)    Ampulla of the uterine tube

R)     Vagina

S)      Fimbria of the uterine tube

n  Answer：Q

 

10.    Which of the following electrolytes participates in action potential phase 0 of sinoatrial node?

P)     Na⁺

Q)    K⁺

R)     Ca²⁺

S)      Mg²⁺

n  Answer：R

 

11.    Which of the following components isn’t contained in bile?

P)     Bile acid

Q)    Digestive enzyme

R)     Cholesterol

S)      Phospholipid

n  Answer：Q

 

12.    Which of the following sense is conducted in posterior funiculus?

P)     Position sense

Q)    Rough tactile sense

R)     Thermal sense

S)      Pressure sense

n  Answer：P

 

13.    Which of the following structures is shaved in LASIK operation?

P)     Lens cortex

Q)    Nucleus of lens

R)     Corneal epithelium

S)      Corneal stroma

n  Answer:：S

 

14.    Which vein does the left testicular vein join?

n  Answer：Left renal vein

 

15.    What is the motor protein in skeletal muscle?

n  Answer：Myosin

 

16.    What is the final metabolite of the purine?

n  Answer：uric acid

 

17.    What infectious disease has mankind succeeded in eradicating for the first time?

n  Answer：Smallpox (smallpox virus)

 

18.    What is the period of 4 to 8 weeks during which the embryos are sensitive to drugs and X-rays?

n  Answer：Organogenesis period

 

19.    Where is vasopressin (ADH) produced?

n  Answer：Hypothalamus

 

20.    What are the sites where ryanodine receptor type 1 is mainly expressed?

n  Answer：Skeletal muscle

 

 

 

④     　　　　　　　　　　　　

1.       Haversian canals are arranged along the long axis of the long bones.

n  Answer：True

 

2.       DNA ligase cleaves DNA double strand.

n  Answer：False

 

3.       Kupffer cells are specialized macrophages found in the liver.

n  Answer：True

 

4.       It is possible to transfuse type O blood into a person with type AB blood.

n  Answer：True

 

5.       Anion gap (AG) increases in diabetic ketoacidosis.

n  Answer：True

 

6.       Increase of agonist amount can’t cause maximum reaction during administration of noncompetitive inhibitor.

n  Answer：True

 

7.       Which of the following is incorrect as a cause of metabolic acidosis?

P)     Renal failure

Q)    Primary hyperparathyroidism

R)     Diarrhea

S)      Airway obstruction

n  Answer：S

 

8.       Which of the following is less relevant to cellular immunity than the others?

P)     Th1 cell

Q)    Th2 cell

R)     Macrophage

S)      CD8⁺ T cell

n  Answer：Q

 

 

 

 

9.       Where is the site of glucose reabsorption in the kidney?

P)     Glomerulus

Q)    Proximal tubule

R)     Distal tubule

S)      Collecting duct

n  Answer：Q

 

10.    Which of the following combines with ions which flows through DHP receptors on cardiac muscle cell?

P)     IP₃ receptor

Q)    Ryanodine receptor

R)     Tropomyosin

S)      Actin

n  Answer：Q

 

11.    Which of the following serum marker increases during obstructive jaundice?

P)     CA15-3

Q)    γ-GTP

R)     ChE

S)      CEA

n  Answer:：Q

 

12.    Which of the following statement is correct?

P)     Angiotensin Ⅱ constricts afferent arteriole

Q)    Angiotensin Ⅱ dilates efferent arteriole

R)     Prostaglandin constricts efferent arteriole

S)      Prostaglandin dilates afferent arteriole

n  Answer:：S

n  Comment：renin-angiotensin-aldosterone system promotes dilation of afferent arteriole and by progesterone and constriction of efferent arteriole by angiotensin Ⅱ and increases CFR.

 

13.    Which of the following nerves is a parasympathetic nerve?

P)     Pudendal nerve

Q)    Superior cervical cardiac nerve

R)     Pelvic splanchnic nerve

S)      Sciatic nerve

n  Answer：R

 

 

14.    What is the structure that shuts down the airway during swallowing?

n  Answer：Epiglottis

 

15.    What electrolyte binds to calmodulin?

n  Answer：Calcium

 

16.    What is the rate limiting enzyme in cholesterol biosynthesis?

n  Answer：HMG-CoA reductase

 

17.    What is the difference between systolic and diastolic blood pressure?

n  Answer：Pulse pressure

 

18.    What is the biological substance that best reflects glomerular filtration rate?

n  Answer：Creatinine

 

19.    What is the nerve which goes through the esophageal hiatus of the diaphragm?

n  Answer：Vagus nerve

 

20.    What is the hormone that causes an increase in basal body temperature?

n  Answer：Progesterone (luteinizing hormone)

 

 

⑤     　　　　　　　　　　　　

1.       Albumin is positively charged.

n  Answer：False

 

2.       Human has 80s ribosomes.

n  Answer：True

 

3.       Hepatitis B virus is an RNA virus.

n  Answer：False

 

4.       Erythrocytes live for a month.

n  Answer：False

 

5.       Atrial diuretic peptide secretion increases due to salt restriction.

n  Answer：False

6.       A daughter of a father with mitochondrial disease definitely develops the same disease.

n  Answer：False

 

7.       Which of the following is the most important function of eccrine sweat glands?

P)     Toxin excretion

Q)    Thermoregulation

R)     Water excretion

S)      Adjusting circulating blood volume

n  Answer：Q

 

8.       Exercise decreases blood flow in which organ?

P)     Brain

Q)    Skeletal muscle

R)     Kidney

S)      Heart

n  Answer：R

 

9.       What is the normal color of cerebrospinal fluid?

P)     Colorless

Q)    Light yellow

R)     Light blue

S)      Red

n  Answer：P

 

10.    Which of the following arteries supply nutrient to the jejunum?

P)     Splenic artery

Q)    Gastroduodenal artery

R)     Superior mesenteric artery

S)      Inferior mesenteric artery

n  Answer: R

 

11.    Which of the following plays a role as a neurotransmitter?

P)     Biotin

Q)    Serotonin

R)     Renin

S)      Pepsin

n  Answer: Q

 

12.    Which of the following test values increases during fulminant hepatitis?

P)     BUN

Q)    Fischer ratio

R)     Blood sugar level

S)      PT-INR

n  Answer: S

 

13.    Which of the following senses is NOT included in into special sensation?

P)     Visual sense

Q)    Taste sense

R)     Temperature sense

S)      Olfactory sense

n  Answer：R

 

14.    What is the space between the two lungs in the chest cavity?

n  Answer：Mediastinum

 

15.    What is the common catabolic pathway for all three major nutrients?

n  Answer：TCA circuit or citric acid circuit or tricarboxylic acid circuit

 

16.    Where does the differentiation of human B cells take place?

n  Answer：(Bone) Marrow

 

17.    What is the name of the blood vessels flowing into the left atrium?

n  Answer：Pulmonary vein

 

18.    What is the cranial nerve that innervates the mimetic muscle?

n  Answer：Facial nerve

 

19.    What is the substance that promotes sleep produced from the pineal gland?

n  Answer：Melatonin

 

20.    What is the substance involved in antegrade axon transport?

n  Answer：Kinesin